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1hgu

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Image:1hgu.png

Template:STRUCTURE 1hgu

Contents

HUMAN GROWTH HORMONE

Template:ABSTRACT PUBMED 009655339

About this Structure

1hgu is a 1 chain structure with sequence from Homo sapiens. The April 2004 RCSB PDB Molecule of the Month feature on Growth Hormone by Shuchismita Dutta and David S. Goodsell is 10.2210/rcsb_pdb/mom_2004_4. Full crystallographic information is available from OCA.

See Also

Reference

  • Gomez-Orellana I, Variano B, Miura-Fraboni J, Milstein S, Paton DR. Thermodynamic characterization of an intermediate state of human growth hormone. Protein Sci. 1998 Jun;7(6):1352-8. PMID:9655339 doi:10.1002/pro.5560070611
  • Kasimova MR, Kristensen SM, Howe PW, Christensen T, Matthiesen F, Petersen J, Sorensen HH, Led JJ. NMR studies of the backbone flexibility and structure of human growth hormone: a comparison of high and low pH conformations. J Mol Biol. 2002 May 3;318(3):679-95. PMID:12054815 doi:10.1016/S0022-2836(02)00137-7
  • Hill EE, Morea V, Chothia C. Sequence conservation in families whose members have little or no sequence similarity: the four-helical cytokines and cytochromes. J Mol Biol. 2002 Sep 6;322(1):205-33. PMID:12215425
  • Duda KM, Brooks CL. Identification of residues outside the two binding sites that are critical for activation of the lactogenic activity of human growth hormone. J Biol Chem. 2003 Jun 20;278(25):22734-9. Epub 2003 Apr 7. PMID:12682073 doi:10.1074/jbc.M212550200

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