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4dsn

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Revision as of 06:54, 6 June 2012 by OCA (Talk | contribs)
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Image:4dsn.png

Template:STRUCTURE 4dsn

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

Template:ABSTRACT PUBMED 22431598

About this Structure

4dsn is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Maurer T, Garrenton LS, Oh A, Pitts K, Anderson DJ, Skelton NJ, Fauber BP, Pan B, Malek S, Stokoe D, Ludlam MJ, Bowman KK, Wu J, Giannetti AM, Starovasnik MA, Mellman I, Jackson PK, Rudolph J, Wang W, Fang G. Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. Proc Natl Acad Sci U S A. 2012 Mar 19. PMID:22431598 doi:10.1073/pnas.1116510109

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OCA

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