4e6d

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Template:STRUCTURE 4e6d

JAK2 kinase (JH1 domain) triple mutant in complex with compound 7

Template:ABSTRACT PUBMED 22591402

About this Structure

4e6d is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Kulagowski J. Identification of Imidazo-pyrrolopyridines as Novel and Potent JAK1 Inhibitors. J Med Chem. 2012 May 16. PMID:22591402 doi:10.1021/jm300438j

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Categories: Homo sapiens | Non-specific protein-tyrosine kinase | Murray, J M. | Jak2 | Kinase | Phosphorylation | Transferase | Transferase-transferase inhibitor complex

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