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3t3c

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Image:3t3c.jpg

Template:STRUCTURE 3t3c

Structure of HIV PR resistant patient derived mutant (comprising 22 mutations) in complex with DRV

Template:ABSTRACT PUBMED 22644035

About this Structure

3t3c is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Kozisek M, Henke S, Saskova KG, Jacobs GB, Schuch A, Buchholz B, Muller V, Krausslich HG, Rezacova P, Konvalinka J, Bodem J. Mutations in HIV-1 gag and pol compensate for the loss of viral fitness caused by a highly mutated protease. Antimicrob Agents Chemother. 2012 May 29. PMID:22644035 doi:10.1128/AAC.00465-12

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