4ax9

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Image:4ax9.jpg

Template:STRUCTURE 4ax9

Human thrombin complexed with Napsagatran, RO0466240

Template:ABSTRACT PUBMED 7966150

About this Structure

4ax9 is a 3 chain structure with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hilpert K, Ackermann J, Banner DW, Gast A, Gubernator K, Hadvary P, Labler L, Muller K, Schmid G, Tschopp TB, et al.. Design and synthesis of potent and highly selective thrombin inhibitors. J Med Chem. 1994 Nov 11;37(23):3889-901. PMID:7966150

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OCA

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