3sie

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Image:3sie.png

Template:STRUCTURE 3sie

Contents

Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors

Template:ABSTRACT PUBMED 21714539

About this Structure

3sie is a 2 chain structure of Phosphodiesterase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Xu Z, Liu Z, Chen T, Chen T, Wang Z, Tian G, Shi J, Wang X, Lu Y, Yan X, Wang G, Jiang H, Chen K, Wang S, Xu Y, Shen J, Zhu W. Utilization of Halogen Bond in Lead Optimization: A Case Study of Rational Design of Potent Phosphodiesterase Type 5 (PDE5) Inhibitors. J Med Chem. 2011 Aug 11;54(15):5607-11. Epub 2011 Jul 14. PMID:21714539 doi:10.1021/jm200644r

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