3spf

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Template:STRUCTURE 3spf

Crystal Structure of Bcl-xL bound to BM501

Template:ABSTRACT PUBMED 22448988

About this Structure

3spf is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Zhou H, Chen J, Meagher JL, Yang CY, Aguilar A, Liu L, Bai L, Cong X, Cai Q, Fang X, Stuckey JA, Wang S. Design of Bcl-2 and Bcl-xL Inhibitors with Subnanomolar Binding Affinities Based upon a New Scaffold. J Med Chem. 2012 May 24;55(10):4664-82. Epub 2012 May 10. PMID:22448988 doi:10.1021/jm300178u

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