4eo8

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Template:STRUCTURE 4eo8

HCV NS5B polymerase inhibitors: Tri-substituted acylhydrazines as tertiary amide bioisosteres

Template:ABSTRACT PUBMED 22664130

About this Structure

4eo8 is a 2 chain structure with sequence from Viruses. Full crystallographic information is available from OCA.

Reference

Canales E, Carlson JS, Appleby T, Fenaux M, Lee J, Tian Y, Tirunagari N, Wong M, Watkins WJ. Tri-substituted acylhydrazines as tertiary amide bioisosteres: HCV NS5B polymerase inhibitors. Bioorg Med Chem Lett. 2012 Jul 1;22(13):4288-92. Epub 2012 May 17. PMID:22664130 doi:10.1016/j.bmcl.2012.05.025

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Retrieved from "http://52.214.119.220/wiki/index.php/4eo8"

Categories: RNA-directed RNA polymerase | Viruses | Appleby, T C. | Canales, E. | Watkins, W J. | Hcv | Ns5b | Polymerase inhibitor | Rna | Rna polymerase | Rna-dependent rna polymerase | Thumb site 2 inhibitor | Transferase-transferase inhibitor complex

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