Ribosomal protein S21

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Image:RPS21.png
Crystal Structure of Ribosomal protein S21 from Escherichia coli (3kc4, chain U)

Template:STRUCTURE 3kc4









Ribosomal protein S21 (RPS21) is one of the 22 proteins which belong to the of the bacterial ribosome. It is found only in eubacteria, plant chloroplasts and mammalian mitochondria. It is involved in the initiation of polypeptide synthesis. The images at the left and at the right correspond to one representative RPS21, i.e. the crystal structure of Ribosomal protein S21 from Escherichia coli (3kc4, chain U).

3D Structures of Ribosomal protein S21

Update December 2011

S21 in small ribosomal subunit

3kc4 – EcRPS21 in 30S ribosomal subunit – Escherichia coli
3i1m, 3i1o, 3df1, 3df3, 2vho, 2vhp, 2avy, 2aw7, 3ofa, 3ofb, 3ofx, 3ofy, 3ofo, 3ofp, 3or9, 3ora - EcRPS21 in 30S ribosomal subunit+16S RRNA
3bbn - RPS21 in 30S ribosomal subunit+16S RRNA – Cryo-EM – spinach


S21 in small ribosomal subunit+tRNA+mRNA

2i2p, 2i2u - EcRPS21 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA


S21 in small ribosomal subunit+P-site tRNA

2wwl - EcRPS21 in 30S ribosomal subunit+Poly-Ala chain+P-site tRNA+mRNA +16S RRNA - Escherichia coli
3i1q - EcRPS21 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA
3i1s, 3i1z, 3i21 - EcRPS21 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA +16S RNA


S21 in small ribosomal subunit+A-site tRNA+P-site tRNA+E-site tRNA

3e1a, 3e1c - EcRPS21 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA


S21 in small ribosomal subunit + antibiotics

2qbb, 2qb9, 1vs5, 1vs7, 2qan, 2qal, 2qou, 2qow, 2qoy, 2qp0, 2z4k, 2z4m, 3oaq, 3oar - EcRPS21 in 30S ribosomal subunit+16S RRNA+ antibiotic


S21 in small ribosomal subunit + ribosome recycling factor

2qbd, 2qbf – EcRPS21 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor
3r8n, 3r8o – EcRPS21 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor + mRNA + tRNA
2qbh, 2qbj - EcRPS21 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+gentamicin


S21 in small ribosomal subunit + elongation factor

3fih - EcRPS21 in 30S ribosomal subunit+A-site tRNA Phe+P-site tRNA+mRNA +16S RRNA+elongation factor TU
3izv – EcRPS21 in 30S ribosomal subunit+A/T-site tRNA Phe +16S RRNA+elongation factor TU
3izw – EcRPS21 in 30S ribosomal subunit+A-site tRNA Phe +mRNA +16S RRNA+elongation factor TU
1s1h - yRPS21 in 40S ribosomal subunit+18S RRNA+elongation factor 2 – Cryo-EM – yeast

S21 in small ribosomal subunit + various proteins

3iz6 – RPS21 in 40S ribosomal subunit +RACK1+18S RRNA – wheat – Cryo-EM
3j00 – EcRPS21 in 30S ribosomal subunit + 16S RRNA + FTSQ + apolipoprotein A-I
2ykr – EcRPS21 + 16S RRNA + GMPPNP + GTPase RSGA
4a2i – EcRPS21 + 16S RRNA + GTPase RSGA – Cryo EM

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Michal Harel, Joel L. Sussman, Alexander Berchansky, Jaime Prilusky

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