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4alg

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Revision as of 07:38, 4 July 2012 by OCA (Talk | contribs)
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Image:4alg.jpg

Template:STRUCTURE 4alg

N-Terminal Bromodomain of Human BRD2 With IBET-151

Template:ABSTRACT PUBMED 22437115

About this Structure

4alg is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Seal J, Lamotte Y, Donche F, Bouillot A, Mirguet O, Gellibert F, Nicodeme E, Krysa G, Kirilovsky J, Beinke S, McCleary S, Rioja I, Bamborough P, Chung CW, Gordon L, Lewis T, Walker AL, Cutler L, Lugo D, Wilson DM, Witherington J, Lee K, Prinjha RK. Identification of a novel series of BET family bromodomain inhibitors: binding mode and profile of I-BET151 (GSK1210151A). Bioorg Med Chem Lett. 2012 Apr 15;22(8):2968-72. Epub 2012 Feb 24. PMID:22437115 doi:10.1016/j.bmcl.2012.02.041

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OCA

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