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3tun

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Template:STRUCTURE 3tun

Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor Chem 1356

Template:ABSTRACT PUBMED 22720744

About this Structure

3tun is a 2 chain structure with sequence from Trypanosoma brucei. Full crystallographic information is available from OCA.

Reference

  • Shibata S, Gillespie JR, Ranade RM, Koh CY, Kim JE, Laydbak JU, Zucker FH, Hol WG, Verlinde CL, Buckner FS, Fan E. Urea-based inhibitors of Trypanosoma brucei methionyl-tRNA synthetase: selectivity and in vivo characterization. J Med Chem. 2012 Jun 21. PMID:22720744 doi:10.1021/jm300303e

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