4feg
From Proteopedia
High-resolution structure of pyruvate oxidase in complex with reaction intermediate 2-hydroxyethyl-thiamin diphosphate carbanion-enamine, crystal A
Template:ABSTRACT PUBMED 22730460
About this Structure
4feg is a 2 chain structure with sequence from Lactobacillus plantarum. Full crystallographic information is available from OCA.
Reference
- Meyer D, Neumann P, Koers E, Sjuts H, Ludtke S, Sheldrick GM, Ficner R, Tittmann K. Unexpected tautomeric equilibria of the carbanion-enamine intermediate in pyruvate oxidase highlight unrecognized chemical versatility of thiamin. Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10867-72. Epub 2012 Jun 22. PMID:22730460 doi:10.1073/pnas.1201280109
Categories: Lactobacillus plantarum | Pyruvate oxidase | Ficner, R. | Koers, E. | Luedtke, S. | Meyer, D. | Neumann, P. | Sheldrick, G M. | Sjuts, H. | Tittmann, K. | Carbanion | Oxidation-reduction | Oxidoreductase | Reaction intermediate | Structure activity relationship | Thiamine diphosphate | Umpolung
