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4feg

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Revision as of 07:26, 11 July 2012 by OCA (Talk | contribs)
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Image:4feg.png

Template:STRUCTURE 4feg

High-resolution structure of pyruvate oxidase in complex with reaction intermediate 2-hydroxyethyl-thiamin diphosphate carbanion-enamine, crystal A

Template:ABSTRACT PUBMED 22730460

About this Structure

4feg is a 2 chain structure with sequence from Lactobacillus plantarum. Full crystallographic information is available from OCA.

Reference

  • Meyer D, Neumann P, Koers E, Sjuts H, Ludtke S, Sheldrick GM, Ficner R, Tittmann K. Unexpected tautomeric equilibria of the carbanion-enamine intermediate in pyruvate oxidase highlight unrecognized chemical versatility of thiamin. Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10867-72. Epub 2012 Jun 22. PMID:22730460 doi:10.1073/pnas.1201280109

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OCA

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