4fat

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Image:4fat.jpg

Template:STRUCTURE 4fat

Ligand-binding domain of GluA2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator

Template:ABSTRACT PUBMED 22735771

About this Structure

4fat is a 1 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Harms JE, Benveniste M, Maclean JK, Partin KM, Jamieson C. Functional analysis of a novel positive allosteric modulator of AMPA receptors derived from a structure-based drug design strategy. Neuropharmacology. 2012 Jun 23. PMID:22735771 doi:10.1016/j.neuropharm.2012.06.008

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OCA

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