This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4fhj
From Proteopedia
Crystal Structure of PI3K-gamma in Complex with Imidazopyridine 2
Template:ABSTRACT PUBMED 22765895
About this Structure
4fhj is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Peterson EA, Boezio AA, Andrews PS, Boezio CM, Bush TL, Cheng AC, Choquette D, Coats JR, Colletti AE, Copeland KW, Dupont M, Graceffa R, Grubinska B, Kim JL, Lewis RT, Liu J, Mullady EL, Potashman MH, Romero K, Shaffer PL, Stanton MK, Stellwagen JC, Teffera Y, Yi S, Cai T, La DS. Discovery and optimization of potent and selective imidazopyridine and imidazopyridazine mTOR inhibitors. Bioorg Med Chem Lett. 2012 Jun 16. PMID:22765895 doi:10.1016/j.bmcl.2012.06.033
Categories: Homo sapiens | Shaffer, P L. | Tang, J. | Yakowec, P. | Atp-binding | Inhibitor | Kinase | P101 | P110 | P84 | Transferase | Transferase-inhibitor complex
