4dt7

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Image:4dt7.png

Template:STRUCTURE 4dt7

Contents

Crystal structure of thrombin bound to the activation domain QEDQVDPRLIDGKMTRRGDS of protein C

Template:ABSTRACT PUBMED 22535660

About this Structure

4dt7 is a 6 chain structure of Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Pozzi N, Barranco-Medina S, Chen Z, Di Cera E. Exposure of R169 controls protein C activation and autoactivation. Blood. 2012 Apr 24. PMID:22535660 doi:10.1182/blood-2012-03-415323
  • Pineda AO, Carrell CJ, Bush LA, Prasad S, Caccia S, Chen ZW, Mathews FS, Di Cera E. Molecular dissection of Na+ binding to thrombin. J Biol Chem. 2004 Jul 23;279(30):31842-53. Epub 2004 May 19. PMID:15152000 doi:http://dx.doi.org/10.1074/jbc.M401756200

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