1x81

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Image:1x81.png

Template:STRUCTURE 1x81

Contents

Farnesyl transferase structure of Jansen compound

Template:ABSTRACT PUBMED 15454228

About this Structure

1x81 is a 2 chain structure of Farnesyltransferase with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

See Also

Reference

  • Li Q, Claiborne A, Li T, Hasvold L, Stoll VS, Muchmore S, Jakob CG, Gu W, Cohen J, Hutchins C, Frost D, Rosenberg SH, Sham HL. Design, synthesis, and activity of 4-quinolone and pyridone compounds as nonthiol-containing farnesyltransferase inhibitors. Bioorg Med Chem Lett. 2004 Nov 1;14(21):5367-70. PMID:15454228 doi:10.1016/j.bmcl.2004.08.012

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