3g6h
From Proteopedia
Contents |
Src Thr338Ile inhibited in the DFG-Asp-Out conformation
Template:ABSTRACT PUBMED 19276351
About this Structure
3g6h is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Gallus gallus. Full crystallographic information is available from OCA.
See Also
Reference
- Seeliger MA, Ranjitkar P, Kasap C, Shan Y, Shaw DE, Shah NP, Kuriyan J, Maly DJ. Equally potent inhibition of c-Src and Abl by compounds that recognize inactive kinase conformations. Cancer Res. 2009 Mar 15;69(6):2384-92. Epub 2009 Mar 10. PMID:19276351 doi:10.1158/0008-5472.CAN-08-3953
Categories: Gallus gallus | Non-specific protein-tyrosine kinase | Kasap, C. | Kuriyan, J. | Maly, D J. | Ranjitkar, P. | Seeliger, M A. | Shah, N P. | Shan, Y. | Shaw, D E. | Atp-binding | Cancer | Dfg-asp-out | Dsa compound | Imatinib resistance | Kinase | Lipoprotein | Myristate | Nucleotide-binding | Phosphoprotein | Proto-oncogene | Sh2 domain | Sh3 domain | Transferase | Tyrosine-protein kinase
