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1x8h

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Image:1x8h.png

Template:STRUCTURE 1x8h

Contents

The Mono-Zinc Carbapenemase CphA (N220G mutant) Shows a Zn(II)- NH2 ARG Coordination

Template:ABSTRACT PUBMED 15588826

About this Structure

1x8h is a 1 chain structure of Beta-lactamase with sequence from Aeromonas hydrophila. Full crystallographic information is available from OCA.

See Also

Reference

  • Garau G, Bebrone C, Anne C, Galleni M, Frere JM, Dideberg O. A metallo-beta-lactamase enzyme in action: crystal structures of the monozinc carbapenemase CphA and its complex with biapenem. J Mol Biol. 2005 Jan 28;345(4):785-95. PMID:15588826 doi:http://dx.doi.org/10.1016/j.jmb.2004.10.070
  • Garau G, Garcia-Saez I, Bebrone C, Anne C, Mercuri P, Galleni M, Frere JM, Dideberg O. Update of the standard numbering scheme for class B beta-lactamases. Antimicrob Agents Chemother. 2004 Jul;48(7):2347-9. PMID:15215079 doi:http://dx.doi.org/10.1128/AAC.48.7.2347-2349.2004
  • Carfi A, Pares S, Duee E, Galleni M, Duez C, Frere JM, Dideberg O. The 3-D structure of a zinc metallo-beta-lactamase from Bacillus cereus reveals a new type of protein fold. EMBO J. 1995 Oct 16;14(20):4914-21. PMID:7588620
  • Aoki S, Iwaida K, Hanamoto N, Shiro M, Kimura E. Guanidine is a Zn(2+)-binding ligand at neutral pH in aqueous solution. J Am Chem Soc. 2002 May 15;124(19):5256-7. PMID:11996552

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