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1rqi

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Template:STRUCTURE 1rqi

Contents

Active Conformation of Farnesyl Pyrophosphate Synthase Bound to Isopentyl Pyrophosphate and Dimethylallyl S-Thiolodiphosphate

Template:ABSTRACT PUBMED 14672944

About this Structure

1rqi is a 2 chain structure of Farnesyl diphosphate synthase with sequence from Escherichia coli. Full crystallographic information is available from OCA.

See Also

Reference

  • Hosfield DJ, Zhang Y, Dougan DR, Broun A, Tari LW, Swanson RV, Finn J. Structural basis for bisphosphonate-mediated inhibition of isoprenoid biosynthesis. J Biol Chem. 2004 Mar 5;279(10):8526-9. Epub 2003 Dec 12. PMID:14672944 doi:10.1074/jbc.C300511200
  • Lo CH, Chang YH, Wright JD, Chen SH, Kan D, Lim C, Liang PH. Combined experimental and theoretical study of long-range interactions modulating dimerization and activity of yeast geranylgeranyl diphosphate synthase. J Am Chem Soc. 2009 Mar 25;131(11):4051-62. PMID:19245203 doi:10.1021/ja808699c

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