3qch

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Image:3qch.png

Template:STRUCTURE 3qch

Contents

Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 3-[(3,4-dichlorobenzyl)sulfanyl]-N-(methylsulfonyl)thiophene-2-carboxamide

Template:ABSTRACT PUBMED 21882820

About this Structure

3qch is a 1 chain structure of Proten tyrosine phosphatase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Sheriff S, Beno BR, Zhai W, Kostich WA, McDonnell PA, Kish K, Goldfarb V, Gao M, Kiefer SE, Yanchunas J, Huang Y, Shi S, Zhu S, Dzierba C, Bronson J, Macor JE, Appiah KK, Westphal RS, O'Connell J, Gerritz SW. Small molecule receptor protein tyrosine phosphatase gamma (RPTPgamma) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop. J Med Chem. 2011 Oct 13;54(19):6548-62. Epub 2011 Sep 20. PMID:21882820 doi:10.1021/jm2003766
[[Category: Twisted mixed beta-sheets flanked by {alpha}-helice]]

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