2wyg
From Proteopedia
Contents |
STRUCTURE AND PROPERTY BASED DESIGN OF FACTOR XA INHIBITORS: PYRROLIDIN-2-ONES WITH MONOARYL P4 MOTIFS
Template:ABSTRACT PUBMED 20006499
About this Structure
2wyg is a 2 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Kleanthous S, Borthwick AD, Brown D, Burns-Kurtis CL, Campbell M, Chaudry L, Chan C, Clarte MO, Convery MA, Harling JD, Hortense E, Irving WR, Irvine S, Pateman AJ, Patikis AN, Pinto IL, Pollard DR, Roethka TJ, Senger S, Shah GP, Stelman GJ, Toomey JR, Watson NS, West RI, Whittaker C, Zhou P, Young RJ. Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with monoaryl P4 motifs. Bioorg Med Chem Lett. 2010 Jan 15;20(2):618-22. Epub 2009 Nov 20. PMID:20006499 doi:10.1016/j.bmcl.2009.11.077
Categories: Coagulation factor Xa | Homo sapiens | Borthwick, A D. | Brown, D. | Burns-Kurtis, C L. | Campbell, M. | Chan, C. | Chaudry, L. | Clarte, M. | Convery, M A. | Harling, J D. | Hortense, E. | Irvine, S. | Irving, W R. | Kleanthous, S. | Pateman, A J. | Patikis, A. | Pinto, I L. | Pollard, D R. | Roethka, T J. | Senger, S. | Shah, G P. | Stelman, G J. | Toomey, J R. | Watson, N S. | Whittaker, C. | Young, R J. | Zhou, P. | Blood clotting | Blood coagulation | Egf-like domain | Hydrolase | Hydroxylation | Serine protease | Zymogen
