1zom

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Template:STRUCTURE 1zom

Contents

Crystal Structure of the Catalytic Domain of Coagulation Factor XI in complex with a peptidomimetic Inhibitor

Template:ABSTRACT PUBMED 17181160

About this Structure

1zom is a 1 chain structure of Factor XIa with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Lin J, Deng H, Jin L, Pandey P, Quinn J, Cantin S, Rynkiewicz MJ, Gorga JC, Bibbins F, Celatka CA, Nagafuji P, Bannister TD, Meyers HV, Babine RE, Hayward NJ, Weaver D, Benjamin H, Stassen F, Abdel-Meguid SS, Strickler JE. Design, synthesis, and biological evaluation of peptidomimetic inhibitors of factor XIa as novel anticoagulants. J Med Chem. 2006 Dec 28;49(26):7781-91. PMID:17181160 doi:10.1021/jm060978s

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