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3tge

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Revision as of 20:10, 25 July 2012 by OCA (Talk | contribs)
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Image:3tge.png

Template:STRUCTURE 3tge

Contents

A novel series of potent and selective PDE5 inhibitor1

Template:ABSTRACT PUBMED 21955943

About this Structure

3tge is a 1 chain structure of Phosphodiesterase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Hughes RO, Maddux T, Joseph Rogier D, Lu S, Walker JK, Jon Jacobsen E, Rumsey JM, Zheng Y, Macinnes A, Bond BR, Han S. Investigation of the pyrazinones as PDE5 inhibitors: Evaluation of regioisomeric projections into the solvent region. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6348-52. Epub 2011 Aug 31. PMID:21955943 doi:10.1016/j.bmcl.2011.08.106

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