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3klf
From Proteopedia
Contents |
Crystal structure of wild-type HIV-1 Reverse Transcriptase crosslinked to a DSDNA with a bound excision product, AZTPPPPA
Template:ABSTRACT PUBMED 20852643
About this Structure
3klf is a 16 chain structure of Reverse transcriptase with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
See Also
Reference
- Tu X, Das K, Han Q, Bauman JD, Clark AD Jr, Hou X, Frenkel YV, Gaffney BL, Jones RA, Boyer PL, Hughes SH, Sarafianos SG, Arnold E. Structural basis of HIV-1 resistance to AZT by excision. Nat Struct Mol Biol. 2010 Oct;17(10):1202-9. Epub 2010 Sep 19. PMID:20852643 doi:10.1038/nsmb.1908
Categories: Human immunodeficiency virus 1 | Arnold, E. | Das, K. | Sarafianos, S G. | Tu, X. | Aid | Azt | Azt resistance mechanism | Azt resistance mutation | Aztp4a | Aztppppa | Dinucleoside tetraphosphate | Dna polymerase | Dna-directed dna polymerase | Endonuclease | Hiv | Hiv-1 reverse transcriptase | Hydrolase | Magnesium | Metal-binding | Multifunctional enzyme | Nrti | Nrti resistance | Nuceleoside inhibitor | Nuclease | P51/p66 | Rna-directed dna polymerase | Thymidine analog mutation | Transferase | Transferase-dna complex | Wild-type
