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1ym4

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Image:1ym4.png

Template:STRUCTURE 1ym4

Contents

Crystal structure of human beta secretase complexed with NVP-AMK640

Template:ABSTRACT PUBMED 16078837

About this Structure

1ym4 is a 6 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Hanessian S, Yun H, Hou Y, Yang G, Bayrakdarian M, Therrien E, Moitessier N, Roggo S, Veenstra S, Tintelnot-Blomley M, Rondeau JM, Ostermeier C, Strauss A, Ramage P, Paganetti P, Neumann U, Betschart C. Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimetics. J Med Chem. 2005 Aug 11;48(16):5175-90. PMID:16078837 doi:10.1021/jm050142+

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OCA

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