2gq2

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Template:STRUCTURE 2gq2

Contents 1 Mycobacterium tuberculosis ThyX-NADP complex 2 About this Structure 3 See Also 4 Reference

Mycobacterium tuberculosis ThyX-NADP complex

Template:ABSTRACT PUBMED 16730023

About this Structure

2gq2 is a 4 chain structure of Thymidylate synthase with sequence from Mycobacterium tuberculosis h37rv. Full crystallographic information is available from OCA.

See Also

• Thymidylate synthase

Reference

• Sampathkumar P, Turley S, Sibley CH, Hol WG. NADP+ expels both the co-factor and a substrate analog from the Mycobacterium tuberculosis ThyX active site: opportunities for anti-bacterial drug design. J Mol Biol. 2006 Jun 30;360(1):1-6. Epub 2006 May 12. PMID:16730023 doi:10.1016/j.jmb.2006.04.061
• Sampathkumar P, Turley S, Ulmer JE, Rhie HG, Sibley CH, Hol WG. Structure of the Mycobacterium tuberculosis flavin dependent thymidylate synthase (MtbThyX) at 2.0A resolution. J Mol Biol. 2005 Oct 7;352(5):1091-104. PMID:16139296 doi:10.1016/j.jmb.2005.07.071