1pwm
From Proteopedia
Contents |
Crystal structure of human Aldose Reductase complexed with NADP and Fidarestat
Template:ABSTRACT PUBMED 15146479
About this Structure
1pwm is a 1 chain structure of Aldose Reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- El-Kabbani O, Darmanin C, Schneider TR, Hazemann I, Ruiz F, Oka M, Joachimiak A, Schulze-Briese C, Tomizaki T, Mitschler A, Podjarny A. Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with Fidarestat and Minalrestat: implications for the binding of cyclic imide inhibitors. Proteins. 2004 Jun 1;55(4):805-13. PMID:15146479 doi:10.1002/prot.20001
- Chen X, Weber I, Harrison RW. Hydration water and bulk water in proteins have distinct properties in radial distributions calculated from 105 atomic resolution crystal structures. J Phys Chem B. 2008 Sep 25;112(38):12073-80. Epub 2008 Aug 28. PMID:18754631 doi:10.1021/jp802795a
Categories: Aldehyde reductase | Homo sapiens | Darmanin, C. | El-Kabbani, O. | Hazemann, I. | Joachimiak, A. | Mitschler, A. | Oka, M. | Podjarny, A. | Ruiz, F. | Schneider, T R. | Schulze-Briese, C. | Tomizaki, T. | Aldose reductase | Atomic resolution | Inhibitor binding | Oxidoreductase | Ternary complex