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3sqh

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Image:3sqh.png

Template:STRUCTURE 3sqh

Contents

Crystal structure of prethrombin-2 mutant S195A in the the open form

Template:ABSTRACT PUBMED 22049947

About this Structure

3sqh is a 1 chain structure of Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Pozzi N, Chen Z, Zapata F, Pelc LA, Barranco-Medina S, Di Cera E. Crystal Structures of Prethrombin-2 Reveal Alternative Conformations under Identical Solution Conditions and the Mechanism of Zymogen Activation. Biochemistry. 2011 Nov 29;50(47):10195-202. Epub 2011 Nov 8. PMID:22049947 doi:10.1021/bi2015019
  • Vijayalakshmi J, Padmanabhan KP, Mann KG, Tulinsky A. The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin. Protein Sci. 1994 Dec;3(12):2254-71. PMID:7756983

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OCA

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