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1wq1

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Template:STRUCTURE 1wq1

Contents

RAS-RASGAP COMPLEX

Template:ABSTRACT PUBMED 9219684

About this Structure

1wq1 is a 2 chain structure of GTPase HRas with sequence from Homo sapiens. The April 2012 RCSB PDB Molecule of the Month feature on Ras Protein by David Goodsell is 10.2210/rcsb_pdb/mom_2012_4. Full crystallographic information is available from OCA.

See Also

Reference

  • Scheffzek K, Ahmadian MR, Kabsch W, Wiesmuller L, Lautwein A, Schmitz F, Wittinghofer A. The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants. Science. 1997 Jul 18;277(5324):333-8. PMID:9219684
  • Souchet M, Poupon A, Callebaut I, Leger I, Mornon J, Bril A, Calmels TP. Functional specificity conferred by the unique plasticity of fully alpha-helical Ras and Rho GAPs. FEBS Lett. 2000 Jul 14;477(1-2):99-105. PMID:10899318
  • Grigorenko BL, Nemukhin AV, Topol IA, Cachau RE, Burt SK. QM/MM modeling the Ras-GAP catalyzed hydrolysis of guanosine triphosphate. Proteins. 2005 Aug 15;60(3):495-503. PMID:15906320 doi:10.1002/prot.20472

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