1ze8

From Proteopedia

proteopedia linkproteopedia link

Template:STRUCTURE 1ze8

Contents 1 Carbonic anhydrase II in complex with a membrane-impermeant sulfonamide inhibitor 2 About this Structure 3 See Also 4 Reference

Carbonic anhydrase II in complex with a membrane-impermeant sulfonamide inhibitor

Template:ABSTRACT PUBMED 16134940

About this Structure

1ze8 is a 1 chain structure of Carbonic anhydrase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Carbonic anhydrase

Reference

• Menchise V, De Simone G, Alterio V, Di Fiore A, Pedone C, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: stacking with Phe131 determines active site binding region of inhibitors as exemplified by the X-ray crystal structure of a membrane-impermeant antitumor sulfonamide complexed with isozyme II. J Med Chem. 2005 Sep 8;48(18):5721-7. PMID:16134940 doi:http://dx.doi.org/10.1021/jm050333c