2bg9

From Proteopedia

proteopedia linkproteopedia link

spinqualitylabelsall models PDB ID 2bg9 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
2bg9, resolution 4.00Å ()
Related:	1l4w, 1ljz, 1oed, 1i9b, 1uv6, 1f3r, 1tor, 1tos
Structural annotation: Resources: InterPro : Ipr002394, Ipr006029, Ipr006202, Ipr006201 Pfam : PF02931, PF02932 UniProt : P02711, Q6S3I0, Q6S3H8, Q6S3H9
Functional annotation: Cellular component: membrane postsynaptic membrane cell junction synapse integral to membrane Biological process: transport ion transport Molecular function: receptor activity extracellular ligand-gated ion channel activity ion channel activity neurotransmitter receptor activity nicotinic acetylcholine-activated cation-selective channel activity
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, RCSB, PDBsum
Coordinates:	save as pdb, mmCIF, xml

Contents 1 REFINED STRUCTURE OF THE NICOTINIC ACETYLCHOLINE RECEPTOR AT 4A RESOLUTION. 2 About this Structure 3 See Also 4 Reference

REFINED STRUCTURE OF THE NICOTINIC ACETYLCHOLINE RECEPTOR AT 4A RESOLUTION.

Template:ABSTRACT PUBMED 15701510

About this Structure

2bg9 is a 5 chain structure of Ion channels with sequence from Torpedo marmorata. The November 2005 RCSB PDB Molecule of the Month feature on Acetylcholine Receptor by David S. Goodsell is 10.2210/rcsb_pdb/mom_2005_11. Full crystallographic information is available from OCA.

See Also

• Ion channels

Reference

• Unwin N. Refined structure of the nicotinic acetylcholine receptor at 4A resolution. J Mol Biol. 2005 Mar 4;346(4):967-89. Epub 2005 Jan 25. PMID:15701510 doi:10.1016/j.jmb.2004.12.031
• Miyazawa A, Fujiyoshi Y, Unwin N. Structure and gating mechanism of the acetylcholine receptor pore. Nature. 2003 Jun 26;423(6943):949-55. PMID:12827192 doi:10.1038/nature01748
• Cheng X, Wang H, Grant B, Sine SM, McCammon JA. Targeted molecular dynamics study of C-loop closure and channel gating in nicotinic receptors. PLoS Comput Biol. 2006 Sep 29;2(9):e134. Epub 2006 Aug 23. PMID:17009865 doi:10.1371/journal.pcbi.0020134
• Tomizawa M, Casida JE. Molecular recognition of neonicotinoid insecticides: the determinants of life or death. Acc Chem Res. 2009 Feb 17;42(2):260-9. PMID:19053239 doi:10.1021/ar800131p