4dfu
From Proteopedia
Contents |
Inhibition of an antibiotic resistance enzyme: crystal structure of aminoglycoside phosphotransferase APH(2")-ID/APH(2")-IVA in complex with kanamycin inhibited with quercetin
Template:ABSTRACT PUBMED 22195561
About this Structure
4dfu is a 2 chain structure of Phosphotransferase with sequence from Enterococcus casseliflavus and Streptomyces kanamyceticus. This structure supersedes the now removed PDB entries and 3r82. Full crystallographic information is available from OCA.
See Also
Reference
- Shakya T, Stogios PJ, Waglechner N, Evdokimova E, Ejim L, Blanchard JE, McArthur AG, Savchenko A, Wright GD. A small molecule discrimination map of the antibiotic resistance kinome. Chem Biol. 2011 Dec 23;18(12):1591-601. PMID:22195561 doi:10.1016/j.chembiol.2011.10.018
Categories: Enterococcus casseliflavus | Streptomyces kanamyceticus | Anderson, W F. | CSGID, Center for Structural Genomics of Infectious Diseases. | Dong, A. | Egorova, E. | Evdokimova, E. | Leo, R Di. | Li, H. | Minasov, G. | Savchenko, A. | Shakya, T. | Stogios, P J. | Wright, G D. | Aminoglycoside phosphotransferase | Aminoglycoside | Antibotic | Center for structural genomics of infectious disease | Csgid | Eukaryotic protein kinase-like fold | Flavanoid | Intracellular | Kanamycin | Kinase | Quercetin | Structural genomic | Transferase | Transferase-antibiotic-inhibitor complex | Transferase-antibotic-inhibitor complex