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3gi3

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Image:3gi3.png

Template:STRUCTURE 3gi3

Contents

Crystal structure of a N-Phenyl-N'-Naphthylurea analog in complex with p38 MAP kinase

Template:ABSTRACT PUBMED 19356929

About this Structure

3gi3 is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Cirillo PF, Hickey ER, Moss N, Breitfelder S, Betageri R, Fadra T, Gaenzler F, Gilmore T, Goldberg DR, Kamhi V, Kirrane T, Kroe RR, Madwed J, Moriak M, Netherton M, Pargellis CA, Patel UR, Qian KC, Sharma R, Sun S, Swinamer A, Torcellini C, Takahashi H, Tsang M, Xiong Z. Discovery and characterization of the N-phenyl-N'-naphthylurea class of p38 kinase inhibitors. Bioorg Med Chem Lett. 2009 May 1;19(9):2386-91. Epub 2009 Mar 26. PMID:19356929 doi:10.1016/j.bmcl.2009.03.104

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