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1tqf

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Revision as of 14:10, 26 July 2012 by OCA (Talk | contribs)
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Image:1tqf.png


PDB ID 1tqf

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1tqf, resolution 1.80Å ()
Ligands:
Gene: BACE1, BACE (Homo sapiens)
Activity: Memapsin 2, with EC number 3.4.23.46
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Contents

Crystal structure of human Beta secretase complexed with inhibitor

Template:ABSTRACT PUBMED 15566281

About this Structure

1tqf is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Coburn CA, Stachel SJ, Li YM, Rush DM, Steele TG, Chen-Dodson E, Holloway MK, Xu M, Huang Q, Lai MT, DiMuzio J, Crouthamel MC, Shi XP, Sardana V, Chen Z, Munshi S, Kuo L, Makara GM, Annis DA, Tadikonda PK, Nash HM, Vacca JP, Wang T. Identification of a small molecule nonpeptide active site beta-secretase inhibitor that displays a nontraditional binding mode for aspartyl proteases. J Med Chem. 2004 Dec 2;47(25):6117-9. PMID:15566281 doi:10.1021/jm049388p

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