1w0e

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Template:STRUCTURE 1w0e

Contents

CRYSTAL STRUCTURE OF HUMAN CYTOCHROME P450 3A4

Template:ABSTRACT PUBMED 15256616

About this Structure

1w0e is a 1 chain structure of Cytochrome P450 with sequence from Homo sapiens. The October 2006 RCSB PDB Molecule of the Month feature on Cytochrome p450 by David S. Goodsell is 10.2210/rcsb_pdb/mom_2006_10. Full crystallographic information is available from OCA.

See Also

Reference

  • Williams PA, Cosme J, Vinkovic DM, Ward A, Angove HC, Day PJ, Vonrhein C, Tickle IJ, Jhoti H. Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone. Science. 2004 Jul 30;305(5684):683-6. Epub 2004 Jul 15. PMID:15256616 doi:http://dx.doi.org/10.1126/science.1099736
  • Moore CD, Shahrokh K, Sontum SF, Cheatham TE 3rd, Yost GS. Improved cytochrome P450 3A4 molecular models accurately predict the Phe215 requirement for raloxifene dehydrogenation selectivity. Biochemistry. 2010 Oct 19;49(41):9011-9. PMID:20812728 doi:10.1021/bi101139q

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