2hoc

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Template:STRUCTURE 2hoc

Contents 1 Crystal structure of the human carbonic anhydrase II in complex with the 5-(4-amino-3-chloro-5-fluorophenylsulfonamido)-1,3,4-thiadiazole-2-sulfonamide inhibitor 2 About this Structure 3 See Also 4 Reference

Crystal structure of the human carbonic anhydrase II in complex with the 5-(4-amino-3-chloro-5-fluorophenylsulfonamido)-1,3,4-thiadiazole-2-sulfonamide inhibitor

Template:ABSTRACT PUBMED 17000110

About this Structure

2hoc is a 1 chain structure of Carbonic anhydrase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Carbonic anhydrase

Reference

• Menchise V, De Simone G, Di Fiore A, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of 5-amino-1,3,4-thiadiazole-2-sulfonamide and 5-(4-amino-3-chloro-5-fluorophenylsulfonamido)-1,3,4-thiadiazole-2-sulfona mide to human isoform II. Bioorg Med Chem Lett. 2006 Dec 15;16(24):6204-8. Epub 2006 Sep 26. PMID:17000110 doi:10.1016/j.bmcl.2006.09.022
• Eriksson AE, Jones TA, Liljas A. Refined structure of human carbonic anhydrase II at 2.0 A resolution. Proteins. 1988;4(4):274-82. PMID:3151019 doi:http://dx.doi.org/10.1002/prot.340040406