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4r1r

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Image:4r1r.png

Template:STRUCTURE 4r1r

Contents

RIBONUCLEOTIDE REDUCTASE R1 PROTEIN WITH SUBSTRATE, GDP AND EFFECTOR DTTP FROM ESCHERICHIA COLI

Template:ABSTRACT PUBMED 9309223

About this Structure

4r1r is a 7 chain structure of Ribonucleotide reductase with sequence from Escherichia coli. Full crystallographic information is available from OCA.

See Also

Reference

  • Eriksson M, Uhlin U, Ramaswamy S, Ekberg M, Regnstrom K, Sjoberg BM, Eklund H. Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding. Structure. 1997 Aug 15;5(8):1077-92. PMID:9309223
  • Bourdon A, Minai L, Serre V, Jais JP, Sarzi E, Aubert S, Chretien D, de Lonlay P, Paquis-Flucklinger V, Arakawa H, Nakamura Y, Munnich A, Rotig A. Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion. Nat Genet. 2007 Jun;39(6):776-80. Epub 2007 May 7. PMID:17486094 doi:10.1038/ng2040

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