2yk2

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Template:STRUCTURE 2yk2

Contents 1 TRICYCLIC SERIES OF HSP90 INHIBITORS 2 About this Structure 3 See Also 4 Reference

TRICYCLIC SERIES OF HSP90 INHIBITORS

Template:ABSTRACT PUBMED 21972823

About this Structure

2yk2 is a 1 chain structure of Heat Shock Proteins with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Heat Shock Proteins

Reference

• Vallee F, Carrez C, Pilorge F, Dupuy A, Parent A, Bertin L, Thompson F, Ferrari P, Fassy F, Lamberton A, Thomas A, Arrebola R, Guerif S, Rohaut A, Certal V, Ruxer JM, Delorme C, Jouanen A, Dumas J, Grepin C, Combeau C, Goulaouic H, Dereu N, Mikol V, Mailliet P, Minoux H. Tricyclic Series of Heat Shock Protein 90 (Hsp90) Inhibitors Part I: Discovery of Tricyclic Imidazo[4,5-c]pyridines as Potent Inhibitors of the Hsp90 Molecular Chaperone. J Med Chem. 2011 Oct 27;54(20):7206-19. Epub 2011 Oct 5. PMID:21972823 doi:10.1021/jm200784m