1tsr

From Proteopedia

proteopedia linkproteopedia link

Template:STRUCTURE 1tsr

Contents 1 P53 CORE DOMAIN IN COMPLEX WITH DNA 2 About this Structure 3 See Also 4 Reference

P53 CORE DOMAIN IN COMPLEX WITH DNA

Template:ABSTRACT PUBMED 8023157

About this Structure

1tsr is a 5 chain structure of P53 with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• P53

Reference

• Cho Y, Gorina S, Jeffrey PD, Pavletich NP. Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations. Science. 1994 Jul 15;265(5170):346-55. PMID:8023157
• Shortle D. Composites of local structure propensities: evidence for local encoding of long-range structure. Protein Sci. 2002 Jan;11(1):18-26. PMID:11742118
• Martin AC, Facchiano AM, Cuff AL, Hernandez-Boussard T, Olivier M, Hainaut P, Thornton JM. Integrating mutation data and structural analysis of the TP53 tumor-suppressor protein. Hum Mutat. 2002 Feb;19(2):149-64. PMID:11793474 doi:10.1002/humu.10032
• Hicks JM, Hsu VL. The extended left-handed helix: a simple nucleic acid-binding motif. Proteins. 2004 May 1;55(2):330-8. PMID:15048824 doi:10.1002/prot.10630