3hk6

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Template:STRUCTURE 3hk6

Contents 1 Crystal structure of murine thrombin mutant W215A/E217A (two molecules in the asymmetric unit) 2 About this Structure 3 See Also 4 Reference

Crystal structure of murine thrombin mutant W215A/E217A (two molecules in the asymmetric unit)

Template:ABSTRACT PUBMED 19586901

About this Structure

3hk6 is a 4 chain structure of Thrombin with sequence from Mus musculus. Full crystallographic information is available from OCA.

See Also

• Thrombin

Reference

• Gandhi PS, Page MJ, Chen Z, Bush-Pelc L, Di Cera E. Mechanism of the anticoagulant activity of thrombin mutant W215A/E217A. J Biol Chem. 2009 Sep 4;284(36):24098-105. Epub 2009 Jul 8. PMID:19586901 doi:10.1074/jbc.M109.025403
• Pineda AO, Chen ZW, Caccia S, Cantwell AM, Savvides SN, Waksman G, Mathews FS, Di Cera E. The anticoagulant thrombin mutant W215A/E217A has a collapsed primary specificity pocket. J Biol Chem. 2004 Sep 17;279(38):39824-8. Epub 2004 Jul 13. PMID:15252033 doi:http://dx.doi.org/10.1074/jbc.M407272200