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2hiz

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Image:2hiz.png

Template:STRUCTURE 2hiz

Contents

Crystal Structure of human beta-secretase (BACE) in the presence of an inhibitor

Template:ABSTRACT PUBMED 17046251

About this Structure

2hiz is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Freskos JN, Fobian YM, Benson TE, Bienkowski MJ, Brown DL, Emmons TL, Heintz R, Laborde A, McDonald JJ, Mischke BV, Molyneaux JM, Moon JB, Mullins PB, Bryan Prince D, Paddock DJ, Tomasselli AG, Winterrowd G. Design of potent inhibitors of human beta-secretase. Part 1. Bioorg Med Chem Lett. 2007 Jan 1;17(1):73-7. Epub 2006 Oct 4. PMID:17046251 doi:10.1016/j.bmcl.2006.09.092

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OCA

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