2ywp

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Template:STRUCTURE 2ywp

Contents

Crystal Structure of CHK1 with a Urea Inhibitor

Template:ABSTRACT PUBMED 16446090

About this Structure

2ywp is a 1 chain structure of Serine/threonine protein kinase with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 2fga. Full crystallographic information is available from OCA.

See Also

Reference

  • Li G, Hasvold LA, Tao ZF, Wang GT, Gwaltney SL 2nd, Patel J, Kovar P, Credo RB, Chen Z, Zhang H, Park C, Sham HL, Sowin T, Rosenberg SH, Lin NH. Synthesis and biological evaluation of 1-(2,4,5-trisubstituted phenyl)-3-(5-cyanopyrazin-2-yl)ureas as potent Chk1 kinase inhibitors. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2293-8. Epub 2006 Jan 30. PMID:16446090 doi:10.1016/j.bmcl.2006.01.028

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