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1a3b

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Image:1a3b.png

Template:STRUCTURE 1a3b

Contents

COMPLEX OF HUMAN ALPHA-THROMBIN WITH THE BIFUNCTIONAL BORONATE INHIBITOR BOROLOG1

Template:ABSTRACT PUBMED 9772168

About this Structure

1a3b is a 3 chain structure of Hirudin and Thrombin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Skordalakes E, Elgendy S, Goodwin CA, Green D, Scully MF, Kakkar VV, Freyssinet JM, Dodson G, Deadman JJ. Bifunctional peptide boronate inhibitors of thrombin: crystallographic analysis of inhibition enhanced by linkage to an exosite 1 binding peptide. Biochemistry. 1998 Oct 13;37(41):14420-7. PMID:9772168 doi:10.1021/bi980225a

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