3h2x

From Proteopedia

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Template:STRUCTURE 3h2x

Contents 1 Crystal Structure of The Human Lymphoid Tyrosine Phosphatase Catalytic Domain 2 About this Structure 3 See Also 4 Reference

Crystal Structure of The Human Lymphoid Tyrosine Phosphatase Catalytic Domain

Template:ABSTRACT PUBMED 19371084

About this Structure

3h2x is a 1 chain structure of Proten tyrosine phosphatase and Tyrosine phosphatase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Proten tyrosine phosphatase
• Tyrosine phosphatase

Reference

• Tsai SJ, Sen U, Zhao L, Greenleaf WB, Dasgupta J, Fiorillo E, Orru V, Bottini N, Chen XS. Crystal structure of the human lymphoid tyrosine phosphatase catalytic domain: insights into redox regulation . Biochemistry. 2009 Jun 9;48(22):4838-45. PMID:19371084 doi:10.1021/bi900166y
• Stanford SM, Krishnamurthy D, Falk MD, Messina R, Debnath B, Li S, Liu T, Kazemi R, Dahl R, He Y, Yu X, Chan AC, Zhang ZY, Barrios AM, Woods VL Jr, Neamati N, Bottini N. Discovery of a novel series of inhibitors of lymphoid tyrosine phosphatase with activity in human T cells. J Med Chem. 2011 Mar 24;54(6):1640-54. Epub 2011 Feb 22. PMID:21341673 doi:10.1021/jm101202j