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3opm

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Image:3opm.png

Template:STRUCTURE 3opm

Contents

Crystal Structure of Human DPP4 Bound to TAK-294

Template:ABSTRACT PUBMED 21764322

About this Structure

3opm is a 4 chain structure of Dipeptidyl peptidase and Farnesyl diphosphate synthase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Banno Y, Miyamoto Y, Sasaki M, Oi S, Asakawa T, Kataoka O, Takeuchi K, Suzuki N, Ikedo K, Kosaka T, Tsubotani S, Tani A, Funami M, Tawada M, Yamamoto Y, Aertgeerts K, Yano J, Maezaki H. Identification of 3-aminomethyl-1,2-dihydro-4-phenyl-1-isoquinolones: a new class of potent, selective, and orally active non-peptide dipeptidyl peptidase IV inhibitors that form a unique interaction with Lys554. Bioorg Med Chem. 2011 Aug 15;19(16):4953-70. Epub 2011 Jun 28. PMID:21764322 doi:10.1016/j.bmc.2011.06.059

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