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1ql8

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Image:1ql8.png

Template:STRUCTURE 1ql8

Contents

FACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN

About this Structure

1ql8 is a 1 chain structure of Trypsin with sequence from Bos taurus. Full crystallographic information is available from OCA.

See Also

Reference

  • Stubbs MT, Reyda S, Dullweber F, Moller M, Klebe G, Dorsch D, Mederski WW, Wurziger H. pH-dependent binding modes observed in trypsin crystals: lessons for structure-based drug design. Chembiochem. 2002 Mar 1;3(2-3):246-9. PMID:11921406
  • Renatus M, Bode W, Huber R, Sturzebecher J, Stubbs MT. Structural and functional analyses of benzamidine-based inhibitors in complex with trypsin: implications for the inhibition of factor Xa, tPA, and urokinase. J Med Chem. 1998 Dec 31;41(27):5445-56. PMID:9876114 doi:10.1021/jm981068g
  • Stubbs MT, Huber R, Bode W. Crystal structures of factor Xa specific inhibitors in complex with trypsin: structural grounds for inhibition of factor Xa and selectivity against thrombin. FEBS Lett. 1995 Nov 13;375(1-2):103-7. PMID:7498454

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