3lnk

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Template:STRUCTURE 3lnk

Contents 1 Structure of BACE bound to SCH743813 2 About this Structure 3 See Also 4 Reference

Structure of BACE bound to SCH743813

Template:ABSTRACT PUBMED 20347593

About this Structure

3lnk is a 2 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Beta secretase

Reference

• Cumming J, Babu S, Huang Y, Carrol C, Chen X, Favreau L, Greenlee W, Guo T, Kennedy M, Kuvelkar R, Le T, Li G, McHugh N, Orth P, Ozgur L, Parker E, Saionz K, Stamford A, Strickland C, Tadesse D, Voigt J, Zhang L, Zhang Q. Piperazine sulfonamide BACE1 inhibitors: design, synthesis, and in vivo characterization. Bioorg Med Chem Lett. 2010 May 1;20(9):2837-42. Epub 2010 Mar 12. PMID:20347593 doi:10.1016/j.bmcl.2010.03.050