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2op3

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Image:2op3.png

Template:STRUCTURE 2op3

Contents

The structure of cathepsin S with a novel 2-arylphenoxyacetaldehyde inhibitor derived by the Substrate Activity Screening (SAS) method

Template:ABSTRACT PUBMED 17469812

About this Structure

2op3 is a 2 chain structure of Cathepsin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Inagaki H, Tsuruoka H, Hornsby M, Lesley SA, Spraggon G, Ellman JA. Characterization and optimization of selective, nonpeptidic inhibitors of cathepsin S with an unprecedented binding mode. J Med Chem. 2007 May 31;50(11):2693-9. Epub 2007 May 1. PMID:17469812 doi:http://dx.doi.org/10.1021/jm070111+

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