3lok
From Proteopedia
Contents |
Drug resistant cSrc kinase domain in complex with covalent inhibitor PD168393
Template:ABSTRACT PUBMED 21080395
About this Structure
3lok is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Gallus gallus. Full crystallographic information is available from OCA.
See Also
Reference
- Kluter S, Simard JR, Rode HB, Grutter C, Pawar V, Raaijmakers HC, Barf TA, Rabiller M, van Otterlo WA, Rauh D. Characterization of irreversible kinase inhibitors by directly detecting covalent bond formation: a tool for dissecting kinase drug resistance. Chembiochem. 2010 Dec 10;11(18):2557-66. PMID:21080395 doi:10.1002/cbic.201000352
Categories: Gallus gallus | Non-specific protein-tyrosine kinase | Gruetter, C. | Rauh, D. | Rode, H B. | Atp-binding | Covalent inhibitor | Drug resistance | Irreversible inhibitor | Kinase | Lipoprotein | Myristate | Nucleotide-binding | Pd168393 | Phosphoprotein | Proto-oncogene | Sh2 domain | Sh3 domain | Src kinase domain | Transferase-transferase inhibitor complex | Tyrosine-protein kinase
