3s7l

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Template:STRUCTURE 3s7l

Contents 1 Pyrazolyl and Thienyl Aminohydantoins as Potent BACE1 Inhibitors 2 About this Structure 3 See Also 4 Reference

Pyrazolyl and Thienyl Aminohydantoins as Potent BACE1 Inhibitors

Template:ABSTRACT PUBMED 21835615

About this Structure

3s7l is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Beta secretase

Reference

• Malamas MS, Erdei J, Gunawan I, Barnes K, Hui Y, Johnson M, Robichaud A, Zhou P, Yan Y, Solvibile W, Turner J, Fan KY, Chopra R, Bard J, Pangalos MN. New pyrazolyl and thienyl aminohydantoins as potent BACE1 inhibitors: Exploring the S2' region. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5164-70. Epub 2011 Jul 23. PMID:21835615 doi:10.1016/j.bmcl.2011.07.057